Splet30. apr. 2024 · Astrocyte plays important roles in the pathogenesis of ischemic stroke and reperfusion injury. They intensively participate in the energy metabolism of the brain, while their heterogeneity and function after ischemic stroke remain controversial. SpletPlatelet-derived growth factor (PDGF) is a family of cysteine-knot-type growth factors that are synthesized in several cells including the brain cells such as the neuronal …
Platelet-derived growth factor receptor α/glial fibrillary acidic ...
SpletAstrocytes invade the developing retina from the optic nerve head, over the axons of retinal ganglion cells (RGCs). RGCs express the platelet-derived growth factor A-chain (PDGF-A) … Splet21. jun. 2024 · OPC population reduction-induced astrocyte maldevelopment. A) DTA mouse genetic construction and Tamoxifen administration. DTA mice were mated with Pdgfra CreER mice to produce Pdgfra CreER:DTA mice, which allows the depletion of OPCs by DTA expression after Tamoxifen treatment. Tamoxifen was administered to mice from … le corbusier buildings in united states
Purification and Culture Methods for Astrocytes - Society for …
Splet19. maj 2024 · Astrocytes that populate the brain’s gray matter, which is densely packed with neuronal cell bodies, are generated by stem cells in the ventricular zone. Stem cells in the outer subventricular zone produce a different suite of astrocytes restricted to the brain’s white matter. —PJH Abstract Spletastrocyte-mediated neuroprotection identifies a novel association with RNA-binding protein ZC3H14 Received for publication, July 24, 2024, and in revised form, November 23, 2024 Published, Papers in Press, November 24, 2024, ... (PDGFRA), as well as the novel RNA-binding protein (RBP) interactors ZC3H14 (zinc finger CCCH-type containing 14 ... Splet01. jun. 2024 · CD49f + hiPSC-astrocytes are thus a valuable resource for investigating human astrocyte function and dysfunction in health and disease. Graphical Abstract. ... but not immature marker NUSAP1 or OPC markers PDGFRA and CSPG4, confirming that sorting on the basis of CD49f enriched for mature astrocytes (Figures 3C, 3D, and S4). how to earn money in google