WebJul 28, 2024 · Cisplatin can cause hearing loss and ringing in the ears. Your hearing will be checked prior to you receiving cisplatin and as needed throughout treatment. Call your doctor or nurse if you have ringing in your ears or if you notice a decrease in your hearing. Allergic Reactions. WebPatients were randomized 1:1 to receive cisplatin-based chemotherapy without (cisplatin alone arm) or with sodium thiosulfate (e.g., Pedmark) (Pedmark + cisplatin arm). The major efficacy outcome measure was hearing loss assessed by American Speech-Language-Hearing Association (ASHA) criteria; hearing was assessed at baseline and 4 weeks …
An optimized, clinically relevant mouse model of cisplatin …
WebChemotherapeutic (antineoplastic) drugs, particularly those containing platinum ( cisplatin and carboplatin ), can cause tinnitus and hearing loss. Hearing loss can be profound and permanent, occurring immediately after the first dose, or can be delayed until several months after completion of treatment. WebNov 12, 2024 · feeling of fullness in the ears fever or chills increased thirst loss of appetite loss of balance loss of hearing lower back or side pain nausea or vomiting painful or … green valley house for sale huntington wv
Cisplatin-Induced Hearing Loss - Fennec Pharmaceuticals
WebThe antineoplastic agent's cisplatin and carboplatin are widely used as they are highly effective. Unfortunately, ototoxicity is a frequently encountered side effect of platinum-based chemotherapy. Clinically, patients generally develop a progressive, bilateral, and irreversible sensorineural hearing loss. WebFeb 28, 2024 · One of the main problems in chemotherapy using platinum drugs as anticancer agents is the resistance phenomenon. Synthesizing and evaluating valid alternative compounds is challenging. This review focuses on the last two years of progress in the studies of platinum (II)- and platinum (IV)-based anticancer complexes. In … WebCisplatin is one of the most effective chemotherapy agents, used in just under half of pediatric cancer cases. Permanent hearing loss is a common side effect of this … fnf minecraft edition