Cisplatin and hyponatremia

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August undefined, 2024

WebBecause hyponatremia was not observed in the subsequent cycle of chemotherapy consisting of weekly paclitaxel and cisplatin, carboplatin was thought to be responsible for the condition. Clinicians should be aware of the possibility that carboplatin may cause SIADH, and should carefully monitor electrolyte balance after chemotherapy. WebCisplatin-Induced Acute Kidney Injury and Renal Salt Wasting Syndrome. A treatment strategy that incorporates both water restrictions and sodium supplementation may be appropriate when differentiating between diagnoses of renal salt wasting syndrome and syndrome of inappropriate antidiuretic hormone secretion.

Cisplatin induced hyponatremia; looking deeper - Renal …

WebA 66-year-old woman with small-cell lung cancer was administered chemo-radiotherapy consisting of cisplatin (CDDP) and etoposide (ETP). From day 3, she developed vomiting and hyponatremia that persisted despite fluid infusion and cortico-steroid administration. Webmostly solid tumors had hyponatremia, and of these, 11% had moderate (sodium [Na] 120–129 mEq/L) to severe (Na , 120 mEq/L) hyponatremia (1). This is disproportionately higher than the hyponatremia prevalence rates of 15%–30% reported for general medicine admissions (2). In cancer patients with nonsolid tumors, rates of hyponatremia are less. mma gyms in indianapolis indiana

Hyponatremia - Symptoms and causes - Mayo Clinic

WebJun 2, 2024 · Background: Cisplatin-associated acute kidney injury (C-AKI) is common. Predictive factors of C-AKI include age > 60 years, hypertension, cisplatin dose, … WebNov 12, 2024 · Very common (10% or more): Anorexia, hyponatremia Uncommon (0.1% to 1%): Hypomagnesemia Frequency not reported: Dehydration, hypokalemia, … WebMay 19, 2024 · Cisplatin treatment may cause hyponatremia through SIADH, related to both higher secretion of and sensitivity to ADH ( 32 ). Nausea and vomiting, which are … mma gyms in grand rapids

An integrated analysis of hyponatremia in cancer patients …

(PDF) Renal Salt Wasting Syndrome due to Carboplatin in

WebFeb 16, 2024 · were treated with cisplatin for various cancers, 8.9% and 1.7% developed grade 3 (serum sodium 120–129mEq/L) and grade 4 ( WebJan 13, 2024 · In addition, significant hyponatremia signals were detected for oesophageal, lung, and renal cancers. Conclusions: Hyponatremia has been reported in women and patients with lung cancer... mma gyms in baliWebcisplatin It is a treatment for a number of different types of cancer. How GC works These chemotherapy drugs destroy quickly dividing cells, such as cancer cells. How you have GC You have these drugs into your bloodstream (intravenously). You might have treatment through a long plastic tube that goes into a large vein in your chest. initial d combined book version

"WebJul 8, 2010 · However, less commonly known is that cisplatin can cause hyponatremia. SIADH is commonly blamed for the cause of hyponatremia in the setting of a patient with … " - Cisplatin and hyponatremia

Cisplatin and hyponatremia

Hyponatremia related to medical anticancer treatment - PubMed

WebDec 16, 2024 · Cisplatin (CDDP; cis-dichlorodiammine platinum [II]) is a non-specific drug of the cell cycle with strong cytotoxicity and broad-spectrum antitumor effects; it is widely used in urogenital system tumors, malignant lymphoma, breast cancer, head and neck cancer, non-small cell lung cancer, etc. ( 1 – 3) Cisplatin-induced nephrotoxicity is … WebNov 10, 2024 · A phase I clinical trial of cisplatin and dose-escalating crolibulin was conducted in patients with advanced solid cancers, including recurrent or metastatic ATC. Of 16 patients with ATC, there was one patient with a complete response and one with stable disease. ... (33%), hyponatremia (29%), anemia (19%), hypertension during infusion …

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WebCisplatin is a well-known chemotherapeutic agent that can be associated with hyponatremia. Mechanisms of cisplatin-induced hyponatremia include renal salt wasting …

WebJun 2, 2024 · Background: Cisplatin-associated acute kidney injury (C-AKI) is common. Predictive factors of C-AKI include age > 60 years, hypertension, cisplatin dose, diabetes, and serum albumin < 3.5g/L. The association between C-AKI and hypokalemia, hypomagnesemia or hyponatremia has not been well characterized to date. WebMay 15, 2004 · Symptoms do not usually appear until the plasma sodium level drops below 120 mEq per L (120 mmol per L) and usually are nonspecific (e.g., headache, …

WebHyponatremia is a common potential complication in cancer patients. It can be related to anticancer medical therapy. Vincristine, vinblastine, cisplatin and cyclophosphamide are the chemotherapeutic agents most frequently associated with hyponatremia. More recently, analogs such as carboplatin and ifosfamide have also been incriminated. WebFeb 1, 1995 · Cisplatin, pharmacology and clinical applications Article Feb 2012 S. Ithimakin View Show abstract A Case of Severe Hyponatremia Caused by Renal Salt Wasting Syndrome in Oropharyngeal Cancer...

WebDec 3, 2014 · Cisplatin-induced hyponatremia in malignancy: comparison between brand-name and generic formulation Cisplatin-induced hyponatremia in malignancy: comparison between brand-name and generic formulation Drug Des Devel Ther doi: 10.2147/DDDT.S71419. eCollection 2014. Authors

WebAug 21, 2014 · The differential diagnosis between RSWS and SIADH for hyponatremic patients is sometimes difficult because of similarities in their clinical features, but careful consideration is needed to make... initial d cityWebMay 17, 2024 · If you have moderate, chronic hyponatremia due to your diet, diuretics or drinking too much water, your doctor may recommend temporarily cutting back on fluids. … initial d crashWebHyponatremia of grade 3 or above developed in 30.7% of the generic CDDP group compared to 15.1% of the brand-name CDDP group ( P =0.011). Multivariate analysis … initial d characters and their carsWebJan 1, 2024 · Univariable analysis revealed a high incidence of hyponatremia in patients receiving cisplatin, three-drug combination regimen, two-drug combination regimen with … initial d discord themeWebMar 1, 2024 · Cisplatin is a well‐known chemotherapeutic agent that can be associated with hyponatremia. It is known to be associated with a multitude of renal disorders including acute kidney injury with reduced glomerular filtration, Fanconi syndrome, and renal tubular acidosis, nephrogenic diabetes insipidus and renal salt wasting syndrome. initial d crewneckWebMay 17, 2024 · Hyponatremia occurs when the concentration of sodium in your blood is abnormally low. Sodium is an electrolyte, and it helps regulate the amount of water that's … initial d characters carsWebcisplatin, docetaxel and 5-fluorouracil-containing chemotherapy who suffered from acute-onset consciousness disturbance due to hyponatremia just after administration of … initial d characters movie