WebJan 21, 2024 · Aging is the predominant risk factor for atherosclerosis, the leading cause of death. Rare smooth muscle cells (SMCs) clonally expand giving rise to up to ∼70% of atherosclerotic plaque cells; however, the effect of age on SMC clonality is not known. Our results indicate that aging induces SMC polyclonality and worsens atherosclerosis … WebAug 28, 2024 · We analyzed 33 enzymes from central carbon metabolism and identified 830 protein-metabolite interactions that were mostly novel, but also included known regulators, substrates, products and their analogs. We validated previously unknown interactions, including two atomic-resolution structures of novel protein-metabolite complexes.

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WebbioRxiv Cold Spring Harbor Laboratory, One Bungtown Road, Cold Spring Harbor, NY 11724 US Email: [email protected] WebThis work has generated interesting insights into nicotine addiction, neurodegenerative disease, and epilepsy. Strains that contain GFP tags on their nicotinic receptors, and that duplicate mutations underlying human epilepsies, are under construction. The epilepsy mutations in nicotinic receptors are also under study in oocyte expression systems. shark tank season 3 products

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WebAffiliations 1 Computational Health Center, Helmholtz Center Munich, Neuherberg, Germany. [email protected].; 2 European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany. [email protected].; 3 Division of Computational Genomics and Systems Genetics, German Cancer Research … Webannouncing Landmark Publication Validates Organ-on-a-Chip Technology for Predictive Toxicology. In a landmark study published in Communications Medicine, part of Nature Portfolio, researchers measured how effective the Emulate human Liver-Chip is at predicting human response to toxic drugs compared to animal and hepatic spheroid models.The … WebDec 29, 2013 · Needles to say, I'm addicted. Visit my DA for more. shark tank season 2 sharks